Article
The role of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 genotypes in alcohol-induced vasospastic angina.
The Tohoku journal of experimental medicine - 1 Apr 1999
Seki T, Okayama H, Isoyama S, Kagaya Y, Shirato K, Munakata K, Kanazawa M, Tamaki K, Hiramoto T, Okayama M, Kasahara S
Abstract excerpt
Alcohol ingestion often provokes attacks in patients with vasospastic angina. Type 2 aldehyde dehydrogenase (ALDH2) deficiency, which is based on a single point mutation (Glu487Lys) of the ALDH2 gene, is common in the Japanese population, but rare among the Caucasian population. We investigated h...
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