Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The role of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 genotypes in alcohol-induced vasospastic angina.

The Tohoku journal of experimental medicine - 1 Apr 1999

Seki T, Okayama H, Isoyama S, Kagaya Y, Shirato K, Munakata K, Kanazawa M, Tamaki K, Hiramoto T, Okayama M, Kasahara S

Abstract excerpt

Alcohol ingestion often provokes attacks in patients with vasospastic angina. Type 2 aldehyde dehydrogenase (ALDH2) deficiency, which is based on a single point mutation (Glu487Lys) of the ALDH2 gene, is common in the Japanese population, but rare among the Caucasian population. We investigated how the genotype of ALDH2 affects the characteristics of alcohol-induced vasospastic angina. Ninety-one patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcohol Dehydrogenase
Share to Alcohol Drinking

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Aldehyde Dehydrogenase

Share to Aldehyde Dehydrogenase, Mitochondrial

Share to Angina Pectoris

Share to ALDH2 gene

Share to Genetic Predisposition to Disease

Share to Point Mutation

Source

Identifiers

PMID: 10503603
DOI: 10.1620/tjem.187.311

Genes

ALDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The role of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 genotypes in alcohol-induced vasospastic angina.PMID 10503603Read ↗

East asian variant of aldehyde dehydrogenase 2 is associated with coronary spastic angina: possible roles of reactive aldehydes and implications of alcohol flushing syndrome.Semantic proximity Read ↗

Involvement of acetaldehyde for full protection against alcoholism by homozygosity of the variant allele of mitochondrial aldehyde dehydrogenase gene in Asians.Semantic proximity Read ↗

The polymorphism in acetaldehyde dehydrogenase 2 gene, causing a substitution of Glu > Lys(504), is not associated with coronary atherosclerosis severity in Han Chinese.Semantic proximity Read ↗

Involvement of genetic polymorphism of alcohol and aldehyde dehydrogenases in individual variation of alcohol metabolism.Semantic proximity Read ↗

Variant Aldehyde Dehydrogenase 2 (ALDH2*2) Is a Risk Factor for Coronary Spasm and ST-Segment Elevation Myocardial Infarction.Semantic proximity Read ↗

Variant Aldehyde Dehydrogenase 2 (ALDH2*2) in East Asians Interactively Exacerbates Tobacco Smoking Risk for Coronary Spasm - Possible Role of Reactive Aldehydes.Semantic proximity Read ↗

Ethanol and acetaldehyde metabolism in chinese with different aldehyde dehydrogenase-2 genotypes.Semantic proximity Read ↗

Effects of aldehyde dehydrogenase-2 genotype on cardiovascular and endocrine responses to alcohol in young Japanese subjects.Semantic proximity Read ↗

[The relationship between aldehyde dehydrogenase-2 gene polymorphisms and efficacy of nitroglycerin].Semantic proximity Read ↗

Effect of aldehyde dehydrogenase-2 genotype on cardiac autonomic nervous responses to moderate alcohol ingestion.Semantic proximity Read ↗

Aldehyde dehydrogenase 2 gene is a risk factor for myocardial infarction in Japanese men.Semantic proximity Read ↗

Role of aldehyde dehydrogenase 2 Glu504lys polymorphism in acute coronary syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.