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Article

Development of a highly accurate, rapid PCR-RFLP genotyping assay for the methylenetetrahydrofolate reductase gene.

Genetic testing - 1 Jan 1999

Sell S M, Lugemwa P R

Abstract excerpt

The C677T mutation of the methylenetetrahydrofolate (MTHFR) gene is a nutrient-oriented, "eco" genetic mutation that is associated with elevated levels of homocysteine and an increased risk for coronary heart disease. The purpose of this study was to optimize and automate an assay for PCR-restriction fragment length polymorphism (RFLP) genotyping of the MTHFR gene. We developed an automated assay for the PCR-RFLP...

Read the complete abstract on PubMed

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Share to Methylenetetrahydrofolate Reductase (NADPH2)

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Source

Identifiers

PMID: 10495928
DOI: 10.1089/109065799316608

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Development of a highly accurate, rapid PCR-RFLP genotyping assay for the methylenetetrahydrofolate reductase gene.PMID 10495928Read ↗

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