Article

Deficiency of Klc2 induces Low-Frequency Sensorineural Hearing Loss in C57BL/6J Mice and Human

2021-03-11

Abstract excerpt

<title>Abstract</title> <p>The transport system in cochlear hair cells (HCs) is important for their function, and the kinesin family of proteins transport numerous cellular cargos via the microtubule network in the cytoplasm. Here, we found that Klc2 (kinesin light chain 2), the light chain of kinesin-1 that mediates cargo binding and regulates kinesin-1 motility, is essential for cochlear function. We generated...

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Literature Corpus work: a1e31d80-684b-561c-9459-6c6532acd15e
DOI: 10.21203/rs.3.rs-277106/v1

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