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Article

Molecular cloning, expression and characterization of the human serine/threonine kinase Akt-3.

European journal of biochemistry - 1 Oct 1999

Masure S, Haefner B, Wesselink J J, Hoefnagel E, Mortier E, Verhasselt P, Tuytelaars A, Gordon R, Richardson A

Abstract excerpt

Akt (also known as PKB or RAC-PK) is an intracellular serine/threonine kinase involved in regulating cell survival. Although this makes it a promising target for the discovery of drugs to treat human cancer, a complicating factor may be the role played by Akt in insulin signalling. Two human isoforms, Akt-1 and Akt-2, have been described previously and a third isoform has been identified in rats (here termed...

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Identifiers

PMID: 10491192
DOI: 10.1046/j.1432-1327.1999.00774.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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