Article
Structural roles of acetylcholinesterase variants in biology and pathology.
European journal of biochemistry - 1 Sept 1999
Grisaru D, Sternfeld M, Eldor A, Glick D, Soreq H
Abstract excerpt
Apart from its catalytic function in hydrolyzing acetylcholine, acetylcholinesterase (AChE) affects cell proliferation, differentiation and responses to various insults, including stress. These responses are at least in part specific to the three C-terminal variants of AChE which are produced by alternative splicing of the single ACHE gene. 'Synaptic' AChE-S constitutes the principal multimeric enzyme in brain...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
