Article
Readthrough acetylcholinesterase: a multifaceted inducer of stress reactions.
Journal of molecular neuroscience : MN - 1 Jan 2006
Zimmerman Gabriel, Soreq Hermona
Abstract excerpt
Stress insults induce hyperexcitation of cholinergic circuits, both peripherally in the sympathetic pathway (Tracey, 2002) and at the central nervous system (CNS) (Sapolsky, 1996). This reaction can serve to ensure survival but might also entail a risk to the hyperactivated neurons. Consequent changes in the expression of a series of proteins related to acetylcholine (ACh) metabolism might protect the organism...
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