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Article

Combinatorial Complexity of 5′ Alternative Acetylcholinesterase Transcripts and Protein Products

1 Jul 2004

Abstract excerpt

To explore the scope and significance of alternate promoter usage and its putative inter-relationship to alternative splicing, we searched expression sequence tags for the 5' region of acetylcholinesterase (ACHE) genes. Three and five novel first exons were identified in human and mouse ACHE genes, respectively. Reverse transcription-PCR and in situ hybridization validated most of the predicted transcripts, and...

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PMID: 15123727
DOI: 10.1074/jbc.m402752200

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