Article
Quantitative association between a newly identified molecular variant in the endothelin-2 gene and human essential hypertension.
Journal of hypertension - 1 Sept 1999
Sharma P, Hingorani A, Jia H, Hopper R, Brown M J
Abstract excerpt
BACKGROUND: Essential hypertension is a multifactorial disease in which the genetic contribution is probably the result of a number of genes acting in combination. Recent work has incriminated endothelin-2 (ET2) as a candidate gene for human essential hypertension. This study sought to (i) determine the existence of any molecular variants in the ET2 gene; (ii) undertake an allelic-association study of any such...
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