Article
Structural analysis and evaluation of the 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) gene in human essential hypertension.
Journal of hypertension - 1 Nov 1998
Brand E, Kato N, Chatelain N, Krozowski Z S, Jeunemaitre X, Corvol P, Plouin P F, Cambien F, Pascoe L, Soubrier F
Abstract excerpt
AIM: Mutations of the 11beta-hydroxysteroid dehydrogenase type 2 (11beta-HSD2) gene cause the syndrome of apparent mineralocorticoid excess, a rare autosomal recessive form of hypertension. We therefore investigated the question of whether variants of the 11beta-HSD2 gene can contribute to geneti...
Topics
- 11-beta-Hydroxysteroid Dehydrogenases
- Alleles
- Base Sequence
- Case-Control Studies
- Data Interpretation, Statistical
- Family Health
- Gene Frequency
- Genes
- Genetic Predisposition to Disease
- Genetic Variation
- Genotype
- Humans
- Hydroxysteroid Dehydrogenases