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Article

Depression and anxiety in Parkinson's disease: possible effect of genetic variation in the serotonin transporter.

Journal of geriatric psychiatry and neurology - 1 Jan 1999

Menza M A, Palermo B, DiPaola R, Sage J I, Ricketts M H

Abstract excerpt

Recently, a functional polymorphism in the promoter region of the serotonin transporter gene has been linked to anxiety. In cell culture, the short allele of this polymorphism synthesizes less serotonin transporter, resulting in a reduction of the removal of serotonin from the synaptic cleft. This pilot study examines depression and anxiety in Parkinson's disease patients as a function of the variation in this...

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Identifiers

PMID: 10483924
DOI: 10.1177/089198879901200202

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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