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Article

Three submicroscopic deletions at the APC locus and their rapid detection by quantitative-PCR analysis.

European journal of human genetics : EJHG - 1 Sept 1999

De Rosa M, Scarano M I, Panariello L, Carlomagno N, Rossi G B, Tempesta A, Borgheresi P, Renda A, Izzo P

Abstract excerpt

We describe three unrelated kindreds, affected by familial adenomatous polyposis (FAP), with 5q submicroscopic deletions that encompass the entire adenomatous polyposis coli (APC) gene and the adjacent DP1 gene. In one family the deletion encompasses also the MCC (mutated in colon cancer) gene. Affected members of these families had dysplastic adenomatous polyps and congenital hypertrophy of the retinal pigment...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10482959
DOI: 10.1038/sj.ejhg.5200344

Genes

APC
FAP
MCC

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Three submicroscopic deletions at the APC locus and their rapid detection by quantitative-PCR analysis.PMID 10482959Read ↗

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