Article
A study on the association of the chromosome 12p13 locus with sporadic late-onset Alzheimer's disease in Chinese.
Dementia and geriatric cognitive disorders - 1 Jan 2009
Li Yan, Chu Leung Wing, Li Zhong, Yik Ping-Yiu, Song You-Qiang
Abstract excerpt
Recent linkage and association studies have implicated the chromosome 12p13 locus as possibly harboring genetic variants predisposed to Alzheimer's disease (AD). We attempted to replicate this association in a Chinese data set comprised of 256 AD cases and 264 age-matched normal controls. A total of 14 single nucleotide polymorphisms (SNPs) were examined. Single marker association revealed the two SNPs in NCAPD2...
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