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Article

Increased bcl-2 expression is associated with primary resistance to chemotherapy in human epithelial ovarian cancer.

Clinical biochemistry - 1 Jul 1999

Kassim S K, Ali H S, Sallam M M, Fayed S T, Seada L S, abd-Elkawy E, Seada M A, Khalifa A

Abstract excerpt

OBJECTIVE: bcl-2, an anti-apoptotic factor, has a role in the pathogenesis of ovarian cancer as well as in resistance to chemotherapy. DESIGN AND METHODS: 20 benign, and 26 malignant epithelial ovarian tissues were analyzed for bcl-2 protein and mutant p53 by enzyme-immunoassay (EIA). Flowcytometric analysis was also performed. Patients of malignant group were followed up to monitor overall survival and primary...

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Identifiers

PMID: 10480447
DOI: 10.1016/s0009-9120(99)00026-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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