Article
Emerging role of p53, bcl-2 and telomerase activity in Egyptian breast cancer patients.
IUBMB life - 1 Aug 2004
Swellam Menha, Ismail Manal, Eissa Sanaa, Hamdy Mohamed, Mokhtar Nadia
Abstract excerpt
Apoptotic cell death represents an important mechanism for the precise regulation of cell numbers, and a defense mechanism against tumor cells. Both bcl-2 and mutant p53 gene products have been involved in apoptotic pathways. On the other hand, cell proliferation capacity and tumorgenesis have been controlled by telomerase. The purpose of our study is to assess the prognostic significance of additional markers...
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