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Article

Associative overdominance, heterozygosity and fitness.

Heredity - 1 Oct 1998

Pamilo P, Pálsson S

Abstract excerpt

Our aim in this study was to examine the power of associative overdominance in creating a correlation between individual heterozygosity and fitness and in maintaining genetic polymorphism at neutral loci. This was undertaken by simulating a diploid model with five chromosomes, each with 1000 loci that could have deleterious mutations linked to neutral markers located on the same chromosomes. The simulations were...

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PMID: 9839436
DOI: 10.1046/j.1365-2540.1998.00395.x

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