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Article

Myosin light chain-2 mutation affects flight, wing beat frequency, and indirect flight muscle contraction kinetics in Drosophila.

The Journal of cell biology - 1 Dec 1992

Warmke J, Yamakawa M, Molloy J, Falkenthal S, Maughan D

Abstract excerpt

We have used a combination of classical genetic, molecular genetic, histological, biochemical, and biophysical techniques to identify and characterize a null mutation of the myosin light chain-2 (MLC-2) locus of Drosophila melanogaster. Mlc2E38 is a null mutation of the MLC-2 gene resulting from a nonsense mutation at the tenth codon position. Mlc2E38 confers dominant flightless behavior that is associated with...

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Identifiers

PMID: 1469046
DOI: 10.1083/jcb.119.6.1523
PMCID: PMC2289745

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