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Article

Rad23 promotes the targeting of proteolytic substrates to the proteasome.

Molecular and cellular biology - 1 Jul 2002

Chen Li, Madura Kiran

Abstract excerpt

Rad23 contains a ubiquitin-like domain (UbL(R23)) that interacts with catalytically active proteasomes and two ubiquitin (Ub)-associated (UBA) sequences that bind Ub. The UBA domains can bind Ub in vitro, although the significance of this interaction in vivo is poorly understood. Rad23 can interfere with the assembly of multi-Ub chains in vitro, and high-level expression caused stabilization of proteolytic...

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Identifiers

PMID: 12052895
DOI: 10.1128/MCB.22.13.4902-4913.2002
PMCID: PMC133919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Rad23 promotes the targeting of proteolytic substrates to the proteasome.PMID 12052895Read ↗

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