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Article

Generation of a Conditional Allele of the Transcription Factor Atonal Homolog 8 (Atoh8).

PloS one - 1 Jan 2016

Ejarque Miriam, Mir-Coll Joan, Gomis Ramon, German Michael S, Lynn Francis C, Gasa Rosa

Abstract excerpt

Atonal Homolog 8 (Atoh8) is a basic helix-loop-helix (bHLH) transcription factor that is highly conserved across species and expressed in multiple tissues during embryogenesis. In the developing pancreas, Atoh8 is expressed in endocrine progenitors but declines in hormone-positive cells, suggesting a role during early stages of the endocrine differentiation program. We previously generated a whole-body Atoh8...

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PMID: 26752640
DOI: 10.1371/journal.pone.0146273
PMCID: PMC4708992

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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