Article
TAMGeS: a Three-array Method for Genotyping of SNPs by a dual-colour approach.
BMC genomics - 9 Jan 2007
Cozza Arianna, Morandin Francesco, Galfrè Silvia Giulia, Mariotti Veronica, Marangoni Roberto, Pellegrini Silvia
Abstract excerpt
BACKGROUND: Many of the most effective high-throughput protocols for SNP genotyping employ microarrays. Genotypes are assessed by comparing the signal intensities that derive from the hybridization of different allele-specific probes labelled either by using four fluorescent dyes, one for each base, or by using only two dyes and investigating the polymorphic alleles two by two on separate arrays. The employment...
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