Article
Simultaneous detection of C282Y and H63D hemochromatosis mutations by dual-color probes.
Molecular diagnosis : a journal devoted to the understanding of human disease through the clinical application of molecular biology - 1 Jun 2000
Phillips M, Meadows C A, Huang M Y, Millson A, Lyon E
Abstract excerpt
BACKGROUND: Hemochromatosis is a common genetic disease, affecting one in every 200 individuals in the United States. A PCR assay was designed using fluorescent melting curve analysis to simultaneously detect the G845-->A (C282Y) and C187-->G (H63D) mutations. The G845-->A and C187-->G loci are d...
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