Article
Effects of a conditional Drosophila PKA mutant on olfactory learning and memory.
Learning & memory (Cold Spring Harbor, N.Y.) - 1 Jan 2000
Li W, Tully T, Kalderon D
Abstract excerpt
The requirement for cAMP-dependent protein kinase (PKA) in associative learning of Drosophila was assessed in mutant flies hemizygous for a cold-sensitive allele, X4, of the DC0 gene, which encodes the major catalytic subunit of PKA. DC0X4 hemizygotes died as third-instar larvae at 18 degrees C, the restrictive temperature, but were viable when raised at 25 degrees C. Shifting adult DC0X4 hemizygotes from 25...
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