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Article

Null EPAC mutants reveal a sequential order of versatile cAMP effects during Drosophila aversive odor learning.

Learning & memory (Cold Spring Harbor, N.Y.) - 1 May 2017

Richlitzki Antje, Latour Philipp, Schwärzel Martin

Abstract excerpt

Here, we define a role of the cAMP intermediate EPAC in Drosophila aversive odor learning by means of null epac mutants. Complementation analysis revealed that EPAC acts downstream from the rutabaga adenylyl cyclase and in parallel to protein kinase A. By means of targeted knockdown and genetic rescue we identified mushroom body Kenyon cells (KCs) as a necessary and sufficient site of EPAC action. We provide...

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Source

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Identifiers

PMID: 28416632
DOI: 10.1101/lm.043646.116
PMCID: PMC5397686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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