Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regional heterogeneity of the astroglial immunoreactive phenotype: effect of lipopolysaccharide.

Journal of neuroscience research - 15 Sept 1999

Morga E, Faber C, Heuschling P

Abstract excerpt

In order to find out whether the concept of regional heterogeneity in astrocytes also applies to the immunoreactive phenotype, we studied cultured primary rat astrocytes originating from five different brain regions (cortex, hippocampus, striatum, septum, and brainstem).We investigated this heterogeneity through the ability of lipopolysaccharide (LPS) to differentially induce several parameters that are known to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Astrocytes
Share to Brain Mapping
Share to Histocompatibility Antigens Class II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intercellular Adhesion Molecule-1

Share to Interferon-gamma

Share to Lipopolysaccharides

Share to Nitric Oxide

Share to Rats, Wistar

Source

Identifiers

PMID: 10467266

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regional heterogeneity of the astroglial immunoreactive phenotype: effect of lipopolysaccharide.PMID 10467266Read ↗

Cultured astrocytes express regional heterogeneity of the immunoreactive phenotype under basal conditions and after gamma-IFN induction.Semantic proximity Read ↗

Astrocyte Heterogeneity: Impact to Brain Aging and DiseaseSemantic proximity Read ↗

A potential gliovascular mechanism for microglial activation: differential phenotypic switching of microglia by endothelium versus astrocytes.Semantic proximity Read ↗

Differential and paradoxical roles of new-generation antidepressants in primary astrocytic inflammationSemantic proximity Read ↗

Japanese encephalitis virus differentially modulates the induction of multiple pro‐inflammatory mediators in human astrocytoma and astroglioma cell‐linesSemantic proximity Read ↗

Crosstalk between macrophages and astrocytes affects proliferation, reactive phenotype and inflammatory response, suggesting a role during reactive gliosis following spinal cord injury.Semantic proximity Read ↗

Interleukin-1, nitric oxide and reactive astrocytes.Semantic proximity Read ↗

Heterogeneity in Synaptogenic Profile of Astrocytes from Different Brain RegionsSemantic proximity Read ↗

Heterogeneity of microglia and TNF signaling as determinants for neuronal death or survival.Semantic proximity Read ↗

Modulation of astrocytic metabolic phenotype by proinflammatory cytokines.Semantic proximity Read ↗

Effects of lipopolysaccharide on glial phenotype and activity of glutamate transporters: Evidence for delayed up-regulation and redistribution of GLT-1.Semantic proximity Read ↗

Interferon-beta induces major histocompatibility complex of class I (MHC-I) expression and a proinflammatory phenotype in cultivated human astrocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.