Japanese encephalitis virus differentially modulates the induction of multiple pro‐inflammatory mediators in human astrocytoma and astroglioma cell‐lines

Abstract excerpt

Astrocytes become activated in response to many CNS pathologies. The process of astrocyte activation remains rather enigmatic and results in so-called reactive gliosis, a reaction with specific structural and functional characteristics. Astrocytes play a vital role in regulating aspects of inflammation and in the homeostatic maintenance of the CNS. However, the responses of different human astroglial cell-lines...

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