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Cytochrome P450c17alpha gene (CYP17) polymorphism predicts use of hormone replacement therapy.

Cancer research - 15 Aug 1999

Feigelson H S, McKean-Cowdin R, Pike M C, Coetzee G A, Kolonel L N, Nomura A M, Le Marchand L, Henderson B E

Abstract excerpt

We investigated whether a polymorphism in the cytochrome P450c17alpha gene (CYP17), which is associated with higher endogenous hormone levels, influences the use of hormone replacement therapy (HRT). The study included 749 postmenopausal women ages 44-75 years at baseline randomly selected from a larger multiethnic cohort. African-American, Japanese, Latina, and white women were included in the study. Women who...

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Identifiers

PMID: 10463580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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