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Article

Complete inhibition of in vivo glioma growth by oncostatin M

1 Mar 2001

Abstract excerpt

We describe here the oncostatin M (OSM)-dependent inhibition of in vivo tumour formation after intracerebral inoculation of glioblastoma cells in mice. We generated human glioblastoma cells transfected with the OSM gene under the control of a tetracycline-response promoter. Upon removal of tetracycline from the medium, cells exhibited a differentiated cell morphology, while proliferation was significantly...

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Identifiers

PMID: 11238743
DOI: 10.1046/j.1471-4159.2001.00202.x

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