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Article

Alteration of frontal EEG asymmetry during tryptophan depletion predicts future depression.

Journal of affective disorders - 1 May 2009

Allen John J B, McKnight Katherine M, Moreno Francisco A, Demaree Heath A, Delgado Pedro L

Abstract excerpt

BACKGROUND: Tryptophan depletion (TD) reduces brain serotonin and may induce acute depressive symptomatology, especially among those with a history of Major Depression. Depressive response to TD among euthymic patients with a history of depression also predicts future depression. Better prediction might result by assessing a putative endophenotype for depressive risk, frontal electroencephalographic (EEG)...

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Source

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Identifiers

PMID: 18801582
DOI: 10.1016/j.jad.2008.08.003
PMCID: PMC2688527

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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