Article
Predominance of Duplicative <i>VSG</i> Gene Conversion in Antigenic Variation in African Trypanosomes
1 Sept 1999
Abstract excerpt
A number of mechanisms have been described by which African trypanosomes undergo the genetic switches that differentially activate their variant surface glycoprotein genes (VSGs) and bring about antigenic variation. These mechanisms have been observed mainly in trypanosome lines adapted, by rapid syringe passaging, to laboratory conditions. Such "monomorphic" lines, which routinely yield only the proliferative...
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