Article
Genetics and specific immune response in allergy to birch pollen and food: evidence of a strong, positive association between atopy and the HLA class II allele HLA-DR7.
The Journal of allergy and clinical immunology - 1 Aug 1999
Sénéchal H, Geny S, Desvaux F X, Busson M, Mayer C, Aron Y, Oster J P, Bessot J C, Peltre G, Pauli G, Swierczewski E
Abstract excerpt
BACKGROUND: In some geographic areas birch pollen represents the most prominent cause for airborne allergic diseases. Up to 70% of patients allergic to birch pollen are hypersensitive to fruits, especially apples. Associations have been found, in some instances, with a sensitivity to aeroallergens and HLA class II genes. OBJECTIVES: We investigated whether susceptibility or resistance to birch pollen allergy with...
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