Article
Effects of core-packing on the structure, function, and mechanics of a four-helix-bundle protein ROP.
Proteins - 1 Sept 1999
Ceruso M A, Grottesi A, Di Nola A
Abstract excerpt
The effects of core-packing on the structure, function and mechanics of the RNA-binding 4-helix-bundle Rop have been studied by molecular dynamics simulations. The structural, dynamical and geometrical properties of the Rop homodimer, (formed by the antiparallel juxtaposition of two helix-turn-helix motifs), have been compared with those of three protein variants described by Munson et al. (Protein Sci,...
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