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Article

Correlation between protein stability and crystal properties of designed ROP variants.

Proteins - 1 Jun 1993

Kokkinidis M, Vlassi M, Papanikolaou Y, Kotsifaki D, Kingswell A, Tsernoglou D, Hinz H J

Abstract excerpt

Six variants of the ROP protein, designed with the aim to analyze by X-ray crystallography loop formation and core packing interactions in 4-alpha-helical bundles, have been purified and a search of their crystallization conditions has been carried out. Five mutants yield crystals that are suitable for medium to high resolution X-ray diffraction studies. For all mutants crystal size, sensitivity to X-irradiation...

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Identifiers

PMID: 8332609
DOI: 10.1002/prot.340160208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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