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Article

Phenotypic analysis of splenocyte subsets following acute morphine treatment in the rat.

Cellular immunology - 1 Aug 1999

Fecho K, Lysle D T

Abstract excerpt

Prior studies by our laboratory demonstrated that a single injection of morphine produces dose-dependent, naltrexone-reversible, suppressive effects in assays of mitogen-stimulated lymphocyte proliferation and natural killer (NK) cell cytotoxicity in the spleen. The present study used flow cytometry to assess directly whether acute morphine treatment produces these immune alterations by altering the leukocyte...

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Identifiers

PMID: 10448013
DOI: 10.1006/cimm.1999.1534

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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