Article
Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease.
Gastroenterology - 1 Feb 2000
Orchard T R, Thiyagaraja S, Welsh K I, Wordsworth B P, Hill Gaston J S, Jewell D P
Abstract excerpt
BACKGROUND & AIMS: The detection of phenotype-determining genes as opposed to disease susceptibility genes requires precise phenotypic characterization of patients. Peripheral arthropathies in inflammatory bowel disease (IBD) are well recognized and are classified with the HLA-B*27-related spondyloarthropathies by the European Spondyloarthropathy Study Group. However, previous HLA studies in IBD have only shown...
Topics
- Colitis, Ulcerative
- Crohn Disease
- Genetic Predisposition to Disease
- Genotype
- HLA-A Antigens
- HLA-B Antigens
- HLA-C Antigens
- HLA-D Antigens
- HLA-DR Antigens
- HLA-DRB1 Chains
- Humans
- Inflammatory Bowel Diseases
- Joint Diseases
- Major Histocompatibility Complex
- Phenotype
- Prohibitins
- Reference Values