Article
Polymorphism of GSTM1 gene in patients with colorectal cancer and colonic polyps.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie - 1 Jul 1999
Gawrońska-Szklarz B, Lubiński J, Kladny J, Kurzawski G, Bielicki D, Wójcicki M, Sych Z, Musial H D
Abstract excerpt
The frequency of the GSTM1 gene in patients with nonpolyposis colorectal cancer (CRC) (n = 70) and in subjects with colonic polyps (n = 27) was evaluated and compared with healthy individuals (n = 145). Patients with CRC were divided into the three groups: patients coming from the families with hereditary nonpolyposis colorectal cancer (HNPCC) (n = 17); patients with a high risk of HNPCC who were referred to as...
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