Article
Genetic polymorphisms of glutathione S-transferase genes and susceptibility to colorectal cancer: a case-control study in an Indian population.
Cancer epidemiology - 1 Feb 2011
Wang Jingwen, Jiang Jing, Zhao Yang, Gajalakshmi Vendhan, Kuriki Kiyonori, Suzuki Sadao, Nagaya Teruo, Nakamura Seiichi, Akasaka Susumu, Ishikawa Hideki, Tokudome Shinkan
Abstract excerpt
BACKGROUND: Susceptibility to sporadic colorectal cancer is multifactorial and arises from interactive combinations of allelic variants in low-penetrance genes and relevant environmental risk factors. Genetic polymorphisms in metabolic enzymes as gene susceptibility factors may modify colorectal cancer risk. We evaluated the risk of colorectal cancer associated with respective or combined glutathione...
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