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Article

Polymorphisms of glutathione-S-transferases M1, T1, P1 and susceptibility to colorectal cancer in a sample of the Tunisian population.

Medical oncology (Northwood, London, England) - 1 Jan 2014

Kassab Asma, Msolly Awatef, Lakhdar Ramzi, Gharbi Olfa, Miled Abdelhédi

Abstract excerpt

In this study, we investigated the associations of polymorphisms in glutathione-S-transferases (GSTs) genes that are GSTM1, GSTT1, and GSTP1, with sporadic colorectal cancer (CRC). Hundred and fifty patients with CRC and 128 healthy controls were genotyped. DNA was isolated from blood samples. Polymorphisms were assessed by polymerase chain reaction-restriction fragment length polymorphism-based methods and...

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Case-Control Studies
Colorectal Neoplasms
Glutathione S-Transferase pi
Glutathione Transferase
Isoleucine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

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Identifiers

PMID: 24254297
DOI: 10.1007/s12032-013-0760-z

Genes

GSTM1
GSTT1
GSTP1

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