The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila.

doi:10.1242/dev.124.12.2409

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Article

The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila.

Development (Cambridge, England) - 1 Jun 1997

McGrail M, Hays T S

Abstract excerpt

During animal development cellular differentiation is often preceded by an asymmetric cell division whose polarity is determined by the orientation of the mitotic spindle. In the fruit fly, Drosophila melanogaster, the oocyte differentiates in a 16-cell syncytium that arises from a cystoblast whi...

Topics

Animals
Cell Differentiation
Cell Division
Cell Polarity
Cytoplasm
Drosophila melanogaster
Dyneins
Female
Germ Cells
Microtubules
Mutation
Oocytes
Spindle Apparatus

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