Chromosome 8p Deletions and 8q Gains are Associated with Tumor Progression and Poor Prognosis in Prostate Cancer

doi:10.1158/1078-0432.ccr-09-1423

Article

Chromosome 8p Deletions and 8q Gains are Associated with Tumor Progression and Poor Prognosis in Prostate Cancer

23 Dec 2009

Abstract excerpt

PURPOSE: Deletions of 8p and gains of 8q belong to the most frequent cytogenetic alterations in prostate cancer. The target genes of these alterations and their biological significance are unknown. EXPERIMENTAL DESIGN: To determine the relationship between chromosome 8 changes, and prostate cancer phenotype and prognosis, a set of 1.954 fully annotated prostate cancers were analyzed in a tissue microarray format...

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Chromosome <i>8p</i> Deletions and <i>8q</i> Gains are Associated with Tumor Progression and Poor Prognosis in Prostate Cancer

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