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Article

Association of the enkephalinase gene with low amplitude P300 waves.

Neuroreport - 2 Aug 1999

Comings D E, Dietz G, Johnson J P, MacMurray J P

Abstract excerpt

Low amplitude of the P300 evoked potential waves has been linked to substance abuse. Defects in opioidergic genes regulating reward pathways have been implicated as risk factors in substance abuse. Since the rate of degradation of enkephalins regulates their CNS level, we focused on the MME gene for metallo-membrane endopeptidase (neutral endopeptidase, enkephalinase). We identified a GT repeat polymorphism 5' to...

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Source

Identifiers

PMID: 10439449
DOI: 10.1097/00001756-199908020-00011

Genes

MME

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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