Article
The essential <i>Staphylococcus aureus</i> gene <i>fmhB</i> is involved in the first step of peptidoglycan pentaglycine interpeptide formation
3 Aug 1999
Abstract excerpt
The factor catalyzing the first step in the synthesis of the characteristic pentaglycine interpeptide in Staphylococcus aureus peptidoglycan was found to be encoded by the essential gene fmhB. We have analyzed murein composition and structure synthesized when fmhB expression is reduced. The endogenous fmhB promoter was substituted with the xylose regulon from Staphylococcus xylosus, which allowed...
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