Article
Identification of an essential gene responsible for D-Asp incorporation in the Lactococcus lactis peptidoglycan crossbridge.
Molecular microbiology - 1 Dec 2006
Veiga Patrick, Piquet Sandra, Maisons Aurélie, Furlan Sylviane, Courtin Pascal, Chapot-Chartier Marie-Pierre, Kulakauskas Saulius
Abstract excerpt
Bacteria such as Lactococcus lactis have D-aspartate (D-Asp) or its amidated derivative D-asparagine (D-Asn), in their peptidoglycan (PG) interpeptide crossbridge. We performed a subtractive genome analysis to identify L. lactis gene yxbA, orthologues of which being present only in bacteria containing D-amino acids in their PG crossbridge, but absent from those that instead insert L-amino acids or glycine....
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