Article
A hereditary genetic marker closely associated with microsatellite instability in lung cancer.
Cancer research - 15 Sept 1995
Ryberg D, Lindstedt B A, Zienolddiny S, Haugen A
Abstract excerpt
Alterations in 5 microsatellite loci were analyzed in tumors from 137 patients with primary non-small cell lung carcinomas that were also genotyped for the Hras1 variable number of tandem repeats (VNTR) locus. Twenty-nine patients (21%) had changes in at least one microsatellite locus. A majority of these cases (24 of 29, 83%) had VNTR alleles classified as rare in the population. The frequency of these rare...
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