A hereditary genetic marker closely associated with microsatellite instability in lung cancer.

Article

A hereditary genetic marker closely associated with microsatellite instability in lung cancer.

Cancer research - 15 Sept 1995

Ryberg D, Lindstedt B A, Zienolddiny S, Haugen A

Abstract excerpt

Alterations in 5 microsatellite loci were analyzed in tumors from 137 patients with primary non-small cell lung carcinomas that were also genotyped for the Hras1 variable number of tandem repeats (VNTR) locus. Twenty-nine patients (21%) had changes in at least one microsatellite locus. A majority...

Topics

Aged
Alleles
Base Sequence
Carcinoma, Non-Small-Cell Lung
DNA, Satellite
Genes, ras
Genetic Markers
Humans
Lung Neoplasms
Middle Aged
Molecular Sequence Data
Mutation

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