Article
Critical aspartic acid residues in pseudouridine synthases.
The Journal of biological chemistry - 6 Aug 1999
Ramamurthy V, Swann S L, Paulson J L, Spedaliere C J, Mueller E G
Abstract excerpt
The pseudouridine synthases catalyze the isomerization of uridine to pseudouridine at particular positions in certain RNA molecules. Genomic data base searches and sequence alignments using the first four identified pseudouridine synthases led Koonin (Koonin, E. V. (1996) Nucleic Acids Res. 24, 2411-2415) and, independently, Santi and co-workers (Gustafsson, C., Reid, R., Greene, P. J., and Santi, D. V. (1996)...
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