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Article

Abnormal DNA methylation and deoxycytosine‐deoxyguanine content in nucleosomes from lymphocytes undergoing apoptosis

1 Aug 1999

Abstract excerpt

Systemic lupus erythematosus (SLE) is characterized by an accelerated apoptosis of peripheral lymphocytes and an impairment of the clearance of apoptotic cells. Since changes in DNA methylation and in deoxycytosine and deoxyguanine (GC) content have been shown to enhance the potential of DNA to activate murine and human B lymphocytes, we tested the capacity of lymphocytes undergoing apoptosis (under conditions...

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PMID: 10428765
DOI: 10.1096/fasebj.13.11.1415

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Source receipt: pubmed, retrieved 7 Sept 2026.

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