Article
Nystatin effects on vacuolar function in Saccharomyces cerevisiae.
Bioscience, biotechnology, and biochemistry - 1 Jun 1999
Bhuiyan M S, Ito Y, Nakamura A, Tanaka N, Fujita K, Fukui H, Takegawa K
Abstract excerpt
The effects of nystatin, a polyene antibiotic, was studied in Saccharomyces cerevisiae by isolating and characterizing nystatin-sensitive mutants. We isolated a number of nystatin-sensitive mutants by ethylmethane sulfonate mutagenesis. One of these mutants, the nss1 mutant, was characterized in detail. The mutant was sensitive to stresses such as high temperature or high concentrations of monovalent and divalent...
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