Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ca2+ signaling and spinocerebellar ataxia.

Biochimica et biophysica acta. Molecular cell research - 1 Nov 2018

Hisatsune Chihiro, Hamada Kozo, Mikoshiba Katsuhiko

Abstract excerpt

Spinocerebellar ataxia (SCA) is a neural disorder, which is caused by degenerative changes in the cerebellum. SCA is primarily characterized by gait ataxia, and additional clinical features include nystagmus, dysarthria, tremors and cerebellar atrophy. Forty-four hereditary SCAs have been identified to date, along with >35 SCA-associated genes. Despite the great diversity and distinct functionalities of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calcium
Share to Calcium Signaling
Share to Cerebellum

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Disease Susceptibility

Share to Endoplasmic Reticulum

Share to Inositol 1,4,5-Trisphosphate Receptors

Share to Purkinje Cells

Share to Spinocerebellar Ataxias

Source

Identifiers

PMID: 29777722
DOI: 10.1016/j.bbamcr.2018.05.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ca2+ signaling and spinocerebellar ataxia.PMID 29777722Read ↗

Disrupted Calcium Signaling in Animal Models of Human Spinocerebellar Ataxia (SCA)Semantic proximity Read ↗

Roles of inositol 1,4,5-trisphosphate receptors in spinocerebellar ataxias.Semantic proximity Read ↗

Emerging pathogenic pathways in the spinocerebellar ataxias.Semantic proximity Read ↗

Deranged Calcium Signaling in Purkinje Cells and Pathogenesis in Spinocerebellar Ataxia 2 (SCA2) and Other AtaxiasSemantic proximity Read ↗

Keeping Our Calcium in Balance to Maintain Our Balance.Semantic proximity Read ↗

Clinical, genetic, molecular, and pathophysiological insights into spinocerebellar ataxia type 1.Semantic proximity Read ↗

Calcium Signaling, PKC Gamma, IP3R1 and CAR8 Link Spinocerebellar Ataxias and Purkinje Cell Dendritic Development.Semantic proximity Read ↗

Autosomal-dominant cerebellar ataxias.Semantic proximity Read ↗

A mutation in the low voltage-gated calcium channel CACNA1G alters the physiological properties of the channel, causing spinocerebellar ataxia.Semantic proximity Read ↗

The spinocerebellar ataxias.Semantic proximity Read ↗

The spinocerebellar ataxias: order emerges from chaos.Semantic proximity Read ↗

ARSACS: Clinical Features, Pathophysiology and iPS-Derived Models.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.