Dally cooperates with Drosophila Frizzled 2 to transduce Wingless signalling.

Abstract excerpt

The Drosophila wingless gene (wg) encodes a protein of the Wnt family and is a critical regulator in many developmental processes. Biochemical studies have indicated that heparan sulphate proteoglycans, consisting of a protein core to which heparan sulphate glycosaminoglycans are attached, are important for Wg function. Here we show that, consistent with these findings, the Drosophila gene sulfateless (sfl),...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amidohydrolases
• Share to Frizzled Receptors
• Share to Heparin