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Article

Polymorphism and signalling of melatonin receptors.

Reproduction, nutrition, development - 1 Jan 2000

Brydon L, Petit L, de Coppet P, Barrett P, Morgan P J, Strosberg A D, Jockers R

Abstract excerpt

Melatonin receptors belong to the superfamily of G protein-coupled receptors. Cloning of Mel1c receptors expressed in Xenopus skin revealed the existence of a polymorphism for these receptors. Heterologous expression of the two allelic isoforms, called Mel1c(alpha) and Mel1c(beta), indicated functional differences in their signalling properties. Both isoforms are coupled to the cAMP and cGMP pathways. However,...

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Identifiers

PMID: 10420434
DOI: 10.1051/rnd:19990304

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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