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Revealing Melatonin’s Mysteries: Receptors, signaling pathways, and therapeutics applications

2023-06-27

Abstract excerpt

Melatonin (5-methoxy-acetyl tryptamine) sleep-inducing hormone, and the pineal gland produces it in response to the circadian clock of darkness. In the body, MT1 and MT2 receptors are mostly found, having an orthosteric pocket and ligand binding determinants. Melatonin acts by binding on melatonin receptors, intracellular proteins, and orphan nuclear receptors. It inhibits adenyl cyclase and activates phospholipas...

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Literature Corpus work
c8b2db6c-5dcb-54ff-8ef2-2e5250cdb966
DOI
10.22541/au.168785293.36265476/v1
Open publication

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