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Article

Targeted disruption of the mouse Mel(1b) melatonin receptor.

Molecular and cellular biology - 1 Feb 2003

Jin Xiaowei, von Gall Charlotte, Pieschl Rick L, Gribkoff Valentin K, Stehle Jorg H, Reppert Steven M, Weaver David R

Abstract excerpt

Two high-affinity, G protein-coupled melatonin receptor subtypes have been identified in mammals. Targeted disruption of the Mel(1a) melatonin receptor prevents some, but not all, responses to the hormone, suggesting functional redundancy among receptor subtypes (Liu et al., Neuron 19:91-102, 1997). In the present work, the mouse Mel(1b) melatonin receptor cDNA was isolated and characterized, and the gene has...

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Identifiers

PMID: 12529409
DOI: 10.1128/MCB.23.3.1054-1060.2003
PMCID: PMC140714

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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